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First Reference: 6th Endowment 5:40
For already had many clans fled eastward, to leave behind the lands of the Nile; hoping that in their wandering they might find another land where the Enoshahim did not dwell; causing that there should enter into Mesopotamia the many clans of the screelings, to camp themselves beside the Tigris and Euphrates.
See: Euphrates, Methuselah I, Sumerian Empire, Tigris
Summary: Mesopotamia refers to a region in western Asia, situated between and near to the Tigris-Euphrates river systems. Scripture describes how Neanderthal clans (screelings) fled the regions of the Nile to that of Mesopotamia, hoping to find land not yet occupied by evolutionary modern humans (Enoshahim). Discovering established clans of Enoshahim in Mesopotamia, Neanderthal clans traveled eastward to eventually settle along the banks of the Indus River (6:5:38-43).
Azrael’s Commentary mentions how after the ascension of Zion (ca 8,770 BCE), Enoch’s son, Methuselah, extended missionary efforts throughout Mesopotamia for forty years, seeking out the righteous and re-uniting the Adamic family (AZC — Methuselah I).